I play guitar and bass too from time to time. I never use amps anymore. I keep my tube amps in storage, I probably will sell them someday. I have a Line6 helix system and a Elliot Transit B for bass. The current band I'm playing mostly keys in and everything goes into the mixer. The practice sound is exactly the same as the gig just not as loud. The guitarist in that band uses a Boss floor pedal GT1000 I believe. I can't express how much I appreciate not hauling heavy amps and speakers into a trailer. I just turned 60 and am having trouble with my knee.
In the 'other' band they use amps on stage and I play way more guitar with them, so to conform I use a carvin power amp and a full range cabinet that looks like an amp. My SP6 goes into a Mackie thump 12 in that band. Too me the bands stage sound sounds like ass to me. But I have heard recordings from out in front and stepped out using a wireless, its dramatically different. But I have come to the conclusion I'm not having fun, I have played with these guys 13 years so I'm torn. Their PA Speakers are very heavy too!
It takes awhile with the Helix to figure out the best sound with all the options available. But when its there you know it and its always the same no matter what volume. The only issue I have with these is sometimes you can get too many choices. The plus side is you can go from the sound of a bluesy vintage tube amp sound from the 1950's to Metallica in with a patch change.