Here's a perfect of example of something else I never tried - two subwoofers. But common sense can still prevail.

Unless one of the subs is in a really screwy place, it's obvious both should have the same polarity. (Not the same as phase.) However, the phase adjustments, if present, can also be tweaked. In that case the goal is to measure the LF response at high resolution, and adjust the phase knobs for maximum output around the crossover frequency. This applies to a single sub with a phase knob too.
--Ethan