I use a few different tools.
I use a USB plantronics headset for skype (which my wife bought since she uses Skype a lot). My apartment is pretty quiet and we have an office setup in one of the rooms, so no need for noise reduction. They have a noise cancellation model which I've heard doesn't work very well. I'm used to these and can wear them all day if needed.
My company uses an AT&T system, it`s noisy to use VOIP so I have the system call my landline and I plug a headphone into the telephone.
I have the bose noise reduction earphones which are quite nice, but I've only used them if I'm trying to do a call in a noisy day, but they should work (it's been a while actually that I've used it). If you have a constant background noise (love taking them in airplanes to kill the turbine rumble) they work really well, if the noise is varying it depends.
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Korg Kronos X73 / ARP Odyssey / Yamaha CS6x / P140 / Motif ES Rack / Akai MPK249 / Roland D-05 / JP-08 / Novation Mininova / NL2X / Waldorf Pulse II
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American Deluxe P-Bass, Yamaha RBX760