Hello,
We just finished an album made mostly of Native instruments. All the guitars use guitar rig 1 or 3 with:
Gratifier for low saturated chords
Twang+screamer+Simple Chorus Ensemble for solo (you or another you)
Gratifier + Quad Delay + Studio reverb for solo (Midnight Underground)
I also like to use the talkwha at 3/4 and assign the footpedal to the "size" component. (Theology I)
You can check the music at
http://www.myspace.com/thelubeckheads